Testing the Effect of Nutrients for The Personalized Nutrition with The Danio Rerio Fish (On the Example of The Nanodessert Nutritional Fermented Dairy Product)

  IJETT-book-cover  International Journal of Engineering Trends and Technology (IJETT)          
  
© 2020 by IJETT Journal
Volume-68 Issue-7
Year of Publication : 2020
Authors : Yuri Georgievich Simakov, Violetta Aleksandrovna Purtskhvanidze, Nadezhda Nikolaevna Omelchuk, Larisa Ivanovna Bychkova, Natalia Alekseevna Golovacheva
DOI :  10.14445/22315381/IJETT-V68I7P203S

Citation 

MLA Style: Yuri Georgievich Simakov, Violetta Aleksandrovna Purtskhvanidze, Nadezhda Nikolaevna Omelchuk, Larisa Ivanovna Bychkova, Natalia Alekseevna Golovacheva.  "Testing the Effect of Nutrients for The Personalized Nutrition with The Danio Rerio Fish (On the Example of The Nanodessert Nutritional Fermented Dairy Product)" International Journal of Engineering Trends and Technology 68.7(2020):13-18. 

APA Style:Yuri Georgievich Simakov, Violetta Aleksandrovna Purtskhvanidze, Nadezhda Nikolaevna Omelchuk, Larisa Ivanovna Bychkova, Natalia Alekseevna Golovacheva. Testing the Effect of Nutrients for The Personalized Nutrition with The Danio Rerio Fish (On the Example of The Nanodessert Nutritional Fermented Dairy Product)  International Journal of Engineering Trends and Technology, 68(7),13-18.

Abstract
The effect of the new Nanodessert nutritional biological product (the Nn product) has been studied on the juvenile Danio rerio laboratory fish, which were used for detecting the stimulating properties of the Nn product on the two important biological functions: the erythropoiesis, and the regeneration of the lost organs. As a result of the morphological and fluorescent histochemical analysis, it has been found that the most intensive regeneration of the fin lobe occurs on day 8 of the experiment. At this time, the growth of the cut-off upper lobes of the caudal fins of the fish that receive the Nn product with the feed is by 42 % greater than that of the regenerate of the fish that do not receive the Nn product. The histochemical studies have shown that in the regenerating caudal fin blastemas under the influence of the substances contained in the Nn product, the amount of RNA also increases, which contributes to increasing the protein biosynthesis and accelerates the restoration of the lost parts of the organs.

Reference

[1] D. Traver, A. Winterer, H.M. Stern, E.A. Mayhall, D.M. Langenau, J.L. Kutok, A.T. Look, L.I. Zon, “Effects of lethal irradiation in zebrafish and rescue by hematopoietic cell transplantation”, Blood, vol. 104(5), pp. 1298–1305, 2004.
[2] P. Niethammer, C. Grabher, A.T. Look, T.J. Mitchison, “A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish”, Cell Death Differ, vol. 1, pp. 431-442, 2009.
[3] M. Oren, “Decision making by p53: Life, death and cancer”, Cell Death Differ, vol. 10(4), pp. 431-442, 2003.
[4] E. Pierce, Gistokhimiya. Moscow: ILL, 1963.
[5] T.V. Kuzina, “Izmeneniya struktury yadra eritrotsitov perifericheskoi krovi promyslovykh ryb Volgo-Kaspiiskogo kanala”, Bulletin of the Moscow Region State University. The Natural Sciences series, vol. 2, pp. 50–56, 2011.
[6] T. Ishida, T. Nakajima, A. Kudo, A. Kawakami, “Phosphorylation of Junb family proteins by the Jun Nterminal kinase supports tissue regeneration in zebrafish”, Dev Biol. vol. 340, pp. 468–479, 2010.
[7] 7. C. Jopling, E. Sleep, M. Raya, M. Marti, A. Raya, J.C.I. Belmonte, “Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation”, Nature, vol. 464, pp. 606-609, 2010.
[8] V.V. Vlasov, E.Y. Rykova, A.A. Ponomariova, I.A. Zaporozhchenko, E.S. Morozkin, N.V. Cherdyntseva, P.P. Laktionov, “Tsirkuliruyushchie mikroRNK krovi pri rake legkogo: perspektivy ispolzovaniya dlya diagnostiki, prognoza i otsenki effektivnosti terapii”, Molecular biology, vol. 49(1), pp. 55–66, 2015.
[9] P.S. Vorozheikin, I.I. Titov, “Veb-server dlya predskazaniya RNK, ikh predshestvennikov i saitov svyazyvaniya”, Molecular biology, vol. 49(5), pp. 846 – 853, 2015.

Keywords
Nanodessert nutritional product, zebrafish, stimulation, erythropoiesis, regeneration, RNA